Waseem Qasim Research Group
Genome editing & Gene Therapy
PUBLICATIONS
Recent genome editing papers:
1: Rasaiyaah J, Georgiadis C, Preece R, Mock U, Qasim W. TCRαβ/CD3 disruption
enables CD3-specific antileukemic T cell immunotherapy. JCI Insight. 2018 Jul
12;3(13). pii: 99442.
https://doi.org/10.1172/jci.insight.99442
2: Georgiadis C, Preece R, Nickolay L, Etuk A, Petrova A, Ladon D, Danyi A,
Humphryes-Kirilov N, Ajetunmobi A, Kim D, Kim JS, Qasim W. Long Terminal Repeat
CRISPR-CAR-Coupled "Universal" T Cells Mediate Potent Anti-leukemic Effects. Mol
Ther. 2018 May 2;26(5):1215-1227. doi: 10.1016/j.ymthe.2018.02.025.
3: Abramowski-Mock U, Delhove JM, Qasim W. Gene Modified T Cell Therapies for
Hematological Malignancies. Hematol Oncol Clin North Am. 2017 Oct;31(5):913-926.
doi: 10.1016/j.hoc.2017.06.005. Review. PubMed PMID: 28895856.
4: Delhove JMKM, Qasim W. Genome-Edited T Cell Therapies. Curr Stem Cell Rep.
2017;3(2):124-136. doi: 10.1007/s40778-017-0077-5. Epub 2017 Apr 18. Review.
PubMed PMID: 28596938; PubMed Central PMCID: PMC5445182.
https://dx.doi.org/10.1007%2Fs40778-017-0077-5
5: Qasim W, Zhan H, Samarasinghe S, Adams S, Amrolia P, Stafford S, Butler K,
Rivat C, Wright G, Somana K, Ghorashian S, Pinner D, Ahsan G, Gilmour K, Lucchini
G, Inglott S, Mifsud W, Chiesa R, Peggs KS, Chan L, Farzeneh F, Thrasher AJ, Vora
A, Pule M, Veys P. Molecular remission of infant B-ALL after infusion of
universal TALEN gene-edited CAR T cells. Sci Transl Med. 2017 Jan 25;9(374). pii:
eaaj2013. doi: 10.1126/scitranslmed.aaj2013.
http://stm.sciencemag.org/content/9/374/eaaj2013.short#login-pane