PUBLICATIONS

Recent genome editing papers:

1: Rasaiyaah J, Georgiadis C, Preece R, Mock U, Qasim W. TCRαβ/CD3 disruption

enables CD3-specific antileukemic T cell immunotherapy. JCI Insight. 2018 Jul

12;3(13). pii: 99442.

https://doi.org/10.1172/jci.insight.99442

 

2: Georgiadis C, Preece R, Nickolay L, Etuk A, Petrova A, Ladon D, Danyi A,

Humphryes-Kirilov N, Ajetunmobi A, Kim D, Kim JS, Qasim W. Long Terminal Repeat

CRISPR-CAR-Coupled "Universal" T Cells Mediate Potent Anti-leukemic Effects. Mol 

Ther. 2018 May 2;26(5):1215-1227. doi: 10.1016/j.ymthe.2018.02.025.

3: Abramowski-Mock U, Delhove JM, Qasim W. Gene Modified T Cell Therapies for

Hematological Malignancies. Hematol Oncol Clin North Am. 2017 Oct;31(5):913-926. 

doi: 10.1016/j.hoc.2017.06.005. Review. PubMed PMID: 28895856.

4: Delhove JMKM, Qasim W. Genome-Edited T Cell Therapies. Curr Stem Cell Rep.

2017;3(2):124-136. doi: 10.1007/s40778-017-0077-5. Epub 2017 Apr 18. Review.

PubMed PMID: 28596938; PubMed Central PMCID: PMC5445182.

https://dx.doi.org/10.1007%2Fs40778-017-0077-5

 

5: Qasim W, Zhan H, Samarasinghe S, Adams S, Amrolia P, Stafford S, Butler K,

Rivat C, Wright G, Somana K, Ghorashian S, Pinner D, Ahsan G, Gilmour K, Lucchini

G, Inglott S, Mifsud W, Chiesa R, Peggs KS, Chan L, Farzeneh F, Thrasher AJ, Vora

A, Pule M, Veys P. Molecular remission of infant B-ALL after infusion of

universal TALEN gene-edited CAR T cells. Sci Transl Med. 2017 Jan 25;9(374). pii:

eaaj2013. doi: 10.1126/scitranslmed.aaj2013.

http://stm.sciencemag.org/content/9/374/eaaj2013.short#login-pane

Contact

W.Qasim@ucl.ac.uk at UCL

Waseem.Qasim@GOSH.NHS.UK for clinical contact

 

 

 

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