Waseem Qasim Research Group

T cells encode antigen specific receptors and are central to the adaptive immune response against infections. The are long lived and maintain immunological memory, as well as having regulatory properties important for the prevention of autoimmunity.  

 

Genes coding for alternative receptors (CARs) can be added to T cell using viral vectors or transposons and the cells then used to target certain forms for blood cancer.

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We have a long track record with lentiviral vectors and gene-editing tools, and have built an expertise in manipulating T cells under GMP conditions, allowing translational studies to rapidly progress into clinical trials.​ 

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Our work is supported by grants from NIHR, MRC, Wellcome Trust, Bloodwise, GOSHCC  and others.